Kirjoittaja Aihe: Acupuncture improves chronic prostatitis/chronic pelvic pain syndrome symptoms  (Luettu 817 kertaa)

Acupuncture improves chronic prostatitis/chronic pelvic pain syndrome symptoms


A recent study showed that multiple sessions of acupuncture therapy led to greater improvements in symptoms of moderate to severe chronic prostatitis/chronic pelvic pain syndrome compared with sham therapy.To get more news about alternative therapy for chronic prostatitis, you can visit our official website.

Improvements in pain, voiding dysfunction, anxiety, depression and quality of life lasted up to 24 weeks following acupuncture treatment, according to the results, which were published in Annals of Internal Medicine.“Pharmacologic therapy has so far failed to reveal universal benefits in patients with chronic prostatitis/chronic pelvic pain syndrome,” Zhishun Liu, MD, PhD, a professor in the department of acupuncture and moxibustion at Guang’anmen Hospital, China Academy of Chinese Medical Sciences, told Healio Primary Care. “The evidence for acupuncture is limited, although it is also recommended in current guidelines.”
Liu and colleagues conducted a multicenter, randomized, sham-controlled trial in 10 tertiary hospitals in China. They randomly assigned 440 men with chronic prostatitis/chronic pelvic pain syndrome in a 1:1 ratio to receive 20 sessions of acupuncture or sham therapy over 8 weeks. The participants were eligible for the trial if they had experienced pain or discomfort in the pelvic region for at least 3 out of the previous 6 months without infection, were aged 18 to 50 years and reported a total score of at least 15 on the NIH Chronic Prostatitis Symptom Index (CPSI).
Liu and colleagues evaluated participants for pain, urinary function, quality of life and erectile function. They followed the participants for 24 weeks after treatment. The primary outcome was the proportion of participants who had a reduction of at least six points from baseline in the NIH-CPSI total score at weeks 8 and 32.

The men who received the acupuncture therapy had a mean age of 35.5 years and a mean baseline NIH-CPSI score of 31. The men who received the sham therapy had a mean age of 36.1 years and a mean baseline NIH-CPSI score of 31.4.

Overall, 414 of the 440 men completed the trial, with 94.1% of men in the acupuncture group and 94.6% in the sham group attending at least 16 sessions.

At week 8, the proportion of responders was 60.6% in the acupuncture group and 36.8% in the sham group, yielding a 21.6 adjusted difference in percentage points (adjusted OR = 2.6; 95% CI, 1.8-4), according to the researchers. At week 32, the proportion of responders was 61.5% in the acupuncture group and 38.3% in the sham group, yielding a 21.1 adjusted difference in percentage points (aOR = 2.6; 95% CI, 1.7-3.9).

Adverse events were more common among men who received acupuncture than sham therapy (9.1% vs. 6.4%), but the researchers reported that there were no serious adverse events in either cohort. Also, there was no significant difference in changes in erectile function at any time point or average urinary flow rates at week 8, according to Liu and colleagues.

“Acupuncture is an effective therapy for [chronic prostatitis/chronic pelvic pain syndrome]. Physicians are suggested to recommend it to their patients in clinic,” Liu said. “We believe that acupuncture is also effective for female patients with pelvic pain, although the evidence is insufficient at present. A randomized controlled trial is on the march to evaluate the effectiveness of acupuncture for pelvic pain among females.”

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is the most frequent form of prostatitis, and has a serious impact on patients' quality of life, and causes severe symptoms. The pain in the pelvic, perineal and penile areas, lower abdominal pain, and pain during urination or ejaculation are the main complaints of CP/CPPS. The underlying complex and unknown pathophysiology of this syndrome have made the management of CP/CPPS and the availability of monotherapy challenging. To identify an effective monotherapy, a plethora of clinical trials failed due to its puzzling etiology. Antibiotics, anti-inflammatory, and a-blockers have been commonly used for the treatment of CP/CPPS, but the desired and complete effects have not been gotten yet. The patients and clinicians are attracted to alternative therapies because of their multi-targeted effects. Attention toward natural compounds effectiveness and safety, supporting the development of a new nutraceutical science. In the alternative remedies for the treatment of prostatic diseases, medicinal herbs, in the form of herb parts or extracts, are getting attention due to their positive effects on prostatic diseases. At present, there is no available detailed literature review about the efficacy of medicinal herbs in the treatment of CP/CPPS. This review aimed to explore the useful medicinal herbs in the treatment of CP/CPPS from different perspectives and their possible mechanism of action in managing CP/CPPS.


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